The personal collection of Henry Pearman – owner of Jaguar specialist Eagle – is due to be auctioned at the Salon Privé sale, taking place on 4 September.
Known as the Stradale Collection, the group includes a number of top road and competition cars – though only road-going models will be sold at the London event.
"It is a truly living collection, so is subject to change from time to time," said Pearman.
The headline lot is a 1931 Bentley 41/2 Litre Blower, which is expected to fetch up to £2.5m. The car is number 25 in the production run – the last of the first batch and one of just 50 built. It was driven for 3000km in the inaugural Blower Bentley International Rally in 2010, which celebrated the model's 80th anniversary at Le Mans.
Also flying the flag for British classics is an Aston Martin DB6 Mk2 Volante, similar to that was lent to Prince William by Prince Charles and driven up the Mall during the Royal Wedding. It is one of only 38 built, just 17 of which were fitted with a manual gearbox. It is expected to achieve up to £920,000.
The sale will also include a number of significant Ferraris, including a 1971 365GTS/4 Daytona Spider, which is estimated to sell for £1.75-2.25m. The car was delivered new to US casino owner William F Harrah and has covered just 3995 miles since, gaining Ferrari Classiche certification in 2009.
Nearly as rare is a Ferrari F50, which is estimated at £600-750,000.
Its predecessor, an F40, is also in the sale and expected to achieve the same sum.
Greg MacLeman is a contributor to and former Features Editor of Classic & Sports Car, and drives a restored and uprated 1974 Triumph 2500TC